Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice

I-Ting Judy Wang, Megan Allen, Darren Goffin, +7

Proceedings of the National Academy of Sciences

Signal Transduction PathwaysAutism Spectrum DisordersEvent-related PotentialsSocial SciencesSignaling Pathway +15

Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage

Xinjian Zhu, Jingde Dong, Bing Han, +6

Frontiers in Cellular Neuroscience

Oxidative DamageEpilepsy-induced Er StressEr StressSocial SciencesOxidative Stress +14

Decreased CREB levels suppress epilepsy

Xinjian Zhu, Xiao Han, Julie A. Blendy, +1

Neurobiology of Disease

Molecular NeuroscienceNeurophysiologyNeurological DisorderNeurologyNeuroscience +2

NMDA receptor NR2B subunits contribute to PTZ-kindling-induced hippocampal astrocytosis and oxidative stress

Xinjian Zhu, Jingde Dong, Kai Shen, +5

Brain Research Bulletin

Reductive StressNeurophysiologyNmda Receptor Nr2bCell DeathPtz-kindling-induced Hippocampal Astrocytosis +8

Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse

Ying Bai, Yuan Zhang, Jun Hua, +9

Scientific Reports

Tight Junction ProteinsCell DeathBbb IntegrityEpigeneticsSocial Sciences +24

Pericytes Contribute to the Disruption of the Cerebral Endothelial Barrier via Increasing VEGF Expression: Implications for Stroke

Ying Bai, Xinjian Zhu, Jie Chao, +11

PLoS ONE

Biomedical EngineeringBbb IntegrityGliomaCerebral Vascular RegulationNeuroinflammation +30

Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression

Yuan Zhang, Xuan Lv, Ying Bai, +7

Journal of Neuroinflammation

NADPH oxidase activation is required for pentylenetetrazole kindling-induced hippocampal autophagy

Xinjian Zhu, Kai Shen, Ying Bai, +4

Free Radical Biology and Medicine

Cell AutophagyMitophagyMolecular NeuroscienceAutophagyNeuroprotection +7

IL-17A Induces MIP-1α Expression in Primary Astrocytes via Src/MAPK/PI3K/NF-kB Pathways: Implications for Multiple Sclerosis

Hongwei Yi, Ying Bai, Xinjian Zhu, +7

Journal of Neuroimmune Pharmacology

InflammationCytokineMedicineSrc/mapk/pi3k/nf-kb PathwaysImmunology +8

COX-2-PGE2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice

Xinjian Zhu, Yuanyuan Yao, Jiurong Yang, +7

International Immunopharmacology

Pathway ContributesNeuropharmacologyBrain InjuryNeuroscienceNeurology +5