Anne Chalumeau

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber, Giacomo Frati, Tristan Félix et al. · Science Advances · 2020 · 131 citations · Full text

Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial

Elisa Magrin, Michaëla Semeraro, Nicolas Hebert et al. · Nature Medicine · 2022 · 99 citations

Gene Therapies, Lentiviral Gene Therapy, Immunodeficiencies +9

Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells

Giulia Pavani, Anna Fabiano, Marine Laurent et al. · Blood Advances · 2021 · 74 citations · Full text

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci et al. · Nature Communications · 2022 · 68 citations · Full text

Clinical Results of the Drepaglobe Trial for Sickle Cell Disease Patients

Elisa Magrin, Alessandra Magnani, Michaëla Semeraro et al. · Blood · 2021 · 19 citations