Concepedia

Giacomo Frati

GF

Statistics

Publications

10

Citations

431

H-Index

10

Active since

2018

Affiliations

Institut des Maladies Génétiques Imagine(Current)

Inserm

Université Paris Cité

Assistance Publique – Hôpitaux de Paris

University of Trento

Giacomo Frati is an author at Institut des Maladies Génétiques Imagine specializing in life sciences, genetics, and sickle cell disease.

Publications per year

2018–2025

10

Publications

10

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Leslie Weber, Giacomo Frati, Tristan Félix et al. · Science Advances · 2020 · 134 citations · Full text

Life Sciences, Genetics, Hematology +17

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci et al. · Nature Communications · 2022 · 71 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease

Sara El Hoss, Sylvie Cochet, Auria Godard et al. · Haematologica · 2020 · 62 citations · Full text

Medicine, Cell Biology, Hematology +15

Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy

Giacomo Frati, Marco Luciani, Vasco Meneghini et al. · Cell Death and Disease · 2018 · 48 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Dermatan sulfate epimerase 1 and dermatan 4-O-sulfotransferase 1 form complexes that generate long epimerized 4-O-sulfated blocks

Emil Tykesson, Antti Hassinen, K Zielińska et al. · Journal of Biological Chemistry · 2018 · 33 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

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