Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

Wenjun Ouyang, Sheila Ranganath, Kathryn Weindel, +4

Immunity

CytokineDevelopmental BiologyAutoimmune DiseaseSignal TransductionLymphocyte Development +10

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells

Brian T. Edelson, Wumesh KC, Richard M. Juang, +14

The Journal of Experimental Medicine

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Isabel Beerman, Deepta Bhattacharya, Sasan Zandi, +4

Proceedings of the National Academy of Sciences

Hsc AgingAdult Stem CellImmunologyMyeloid NeoplasiaHematopoietic Stem Cell +15

<i>Zbtb46</i> expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

Ansuman T. Satpathy, Wumesh KC, Jörn C. Albring, +5

The Journal of Experimental Medicine

Lymphocyte DevelopmentAdaptive Immune SystemInnate Immune SystemImmunologyImmune Regulation +22

Efficient Transplantation via Antibody-Based Clearance of Hematopoietic Stem Cell Niches

Agnieszka Czechowicz, Daniel Kraft, Irving L. Weissman, +1

Science

Cell TherapyImmunologyImmunotherapyStem Cell MobilizationStem Cell Transplantation +15

Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity

Tyler J. Ripperger, Jennifer L. Uhrlaub, Makiko Watanabe, +34

Immunity

VaccinationViral EvolutionViral DiagnosticsMedicineVaccine Target +8

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

Matthew A. Inlay, Deepta Bhattacharya, Debashis Sahoo, +6

Genes & Development

Lymphocyte DevelopmentEarliest StageCell ProliferationCommon Lymphoid ProgenitorsCell Specialization +19

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells

Chance John Luckey, Deepta Bhattacharya, Ananda W. Goldrath, +3

Proceedings of the National Academy of Sciences

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

Wing Y. Lam, Amy M. Becker, Krista Kennerly, +13

Immunity

MitophagySignal TransductionMitochondrial FunctionPhysiologyImmunology +7

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, +2

The Journal of Experimental Medicine

Adaptive Immune SystemHumoral ResponseImmunologyViral PathogenesisAntigen Processing +15