Rowena S. Lewis

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

Nathalie Uwamahoro, Jiyoti Verma‐Gaur, Hsin‐Hui Shen et al. · mBio · 2014 · 256 citations · Full text

Kills Macrophages, Microbial Pathogens, Fungal Cell Biology +18

Mitochondrial apoptosis is dispensable for <scp>NLRP</scp> 3 inflammasome activation but non‐apoptotic caspase‐8 is required for inflammasome priming

Ramanjaneyulu Allam, Kate E. Lawlor, Eric Yu et al. · EMBO Reports · 2014 · 240 citations · Full text

The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

Zhihe Kuang, Rowena S. Lewis, Joan Curtis et al. · The Journal of Cell Biology · 2010 · 100 citations · Full text

Structural Basis for Par-4 Recognition by the SPRY Domain- and SOCS Box-Containing Proteins SPSB1, SPSB2, and SPSB4

P. Filippakopoulos, Andrew Low, Timothy Sharpe et al. · Journal of Molecular Biology · 2010 · 66 citations · Full text

Spry Domain-, Protein Assembly, Biomolecular Structure Prediction +19