Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

Xingxing Kong, Rui Wang, Yuan Xue, +5

PLoS ONE

A Smooth Muscle-Like Origin for Beige Adipocytes

Jonathan Z. Long, Katrin J. Svensson, Linus Tsai, +10

Cell Metabolism

Molecular PhysiologyDevelopmental BiologyAdipose TissuePhysiologyTissue Physiology +6

IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α

Xingxing Kong, Alexander S. Banks, Tiemin Liu, +13

Cell

Transcriptional RegulationMolecular RegulationGene RegulationGene ExpressionMedicine +2

Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis

Kevin W. Williams, Tiemin Liu, Xingxing Kong, +17

Cell Metabolism

Energy HomeostasisMolecular NeuroscienceMolecular PhysiologySignal TransductionNeurophysiology +13

Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin

Xingxing Kong, Ting Yao, Peng Zhou, +9

Cell Metabolism

Metabolic SyndromeEnergy HomeostasisBody CompositionMolecular PhysiologySkeletal Muscle +10

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

Lawrence Kazak, Edward T. Chouchani, Irina G. Stavrovskaya, +12

Proceedings of the National Academy of Sciences

IRF3 promotes adipose inflammation and insulin resistance and represses browning

Manju Kumari, Xun Wang, Louise Lantier, +9

Journal of Clinical Investigation

Metabolic DisorderImmunologyImmune RegulationRenal InflammationInsulin Signaling +24

PGC-1β-Regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERRα

Di Shao, Yang Liu, Xiaojun Liu, +10

Mitochondrion

Mitochondrial BiogenesisMitochondrial FunctionCell SignalingGeneticsMedicine +6

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

Eric D. Berglund, Tiemin Liu, Xingxing Kong, +10

Nature Neuroscience

Energy HomeostasisNeurophysiologyMelanocortin 4PhysiologyNeuroendocrine Mechanism +8

Interferon Regulatory Factor 4 Regulates Obesity-Induced Inflammation Through Regulation of Adipose Tissue Macrophage Polarization

Jun Eguchi, Xingxing Kong, Masafumi Tenta, +3

Diabetes

Primary MacrophagesImmunologyImmune RegulationAdipose Tissue MacrophagesInsulin Signaling +16