Luis Fonseca‐Ornelas

The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle et al. · PLoS Biology · 2017 · 212 citations · Full text

Mitophagy, Sirtuin Genes, Immunology +18

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

Raquel Pinho, Isabel Paiva, Kristina Gotovac et al. · Human Molecular Genetics · 2018 · 177 citations · Full text

Genetics, Cell Cycle, Transcriptional Regulation +16

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease

Lars Tatenhorst, Katrin Eckermann, Vivian Dambeck et al. · Acta Neuropathologica Communications · 2016 · 162 citations · Full text

Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity

Nagendran Ramalingam, Shan‐Xue Jin, Tim E. Moors et al. · npj Parkinson s Disease · 2023 · 134 citations · Full text

Small molecule-mediated stabilization of vesicle-associated helical α-synuclein inhibits pathogenic misfolding and aggregation

Luis Fonseca‐Ornelas, Sybille E Eisbach, Maria Paulat et al. · Nature Communications · 2014 · 103 citations · Full text

Small Molecule-mediated Stabilization, Neurodegenerative Diseases, Protein Function +9