Nagendran Ramalingam

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

Saranna Fanning, Aftabul Haque, Thibaut Imberdis et al. · Molecular Cell · 2018 · 276 citations · Full text

Neurodegenerative Diseases, Biochemistry, Lipidomic Analysis +6

Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity

Nagendran Ramalingam, Shan‐Xue Jin, Tim E. Moors et al. · npj Parkinson s Disease · 2023 · 134 citations · Full text

Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells

Ulf Dettmer, Nagendran Ramalingam, Victoria E. von Saucken et al. · Human Molecular Genetics · 2017 · 99 citations · Full text

Amphipathic Helix, Molecular Biology, Cellular Neurobiology +18

Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase

Thibaut Imberdis, Joseph Negri, Nagendran Ramalingam et al. · Proceedings of the National Academy of Sciences · 2019 · 98 citations · Full text

Proteinlipid Interaction, Stearoyl-coa Desaturase, Molecular Biology +18

Phospholipids regulate localization and activity of mDia1 formin

Nagendran Ramalingam, Hongxia Zhao, Dennis Breitsprecher et al. · European Journal of Cell Biology · 2010 · 73 citations

Proteinlipid Interaction, Mdia1 Formin, Biochemistry +2