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Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

Saranna Fanning, Aftabul Haque, Thibaut Imberdis, Valeriya Baru, M. Inmaculada Barrasa, Silke Nuber, Daniel J. Termine, Nagendran Ramalingam, Gary P. H. Ho, Tallie Noble,

Molecular Cell · 2018 · 294 citations · 77 references

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77

α-Synuclein Locus Triplication Causes Parkinson's Disease

Andrew Singleton, Matthew J. Farrer, Janel Johnson et al. · Science · 2003 · 4.4K citations

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Direct conversion of fibroblasts to functional neurons by defined factors

Thomas Vierbuchen, Austin Ostermeier, Zhiping P. Pang et al. · Nature · 2010 · 3K citations

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Triglyceride accumulation protects against fatty acid-induced lipotoxicity

Laura Listenberger, Xianlin Han, Sarah E. Lewis et al. · Proceedings of the National Academy of Sciences · 2003 · 2.1K citations · Full text

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Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

Yingsha Zhang, ChangHui Pak, Yan Han et al. · Neuron · 2013 · 1.8K citations · Full text

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Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes

W. Sean Davidson, Ana Jonas, David F. Clayton et al. · Journal of Biological Chemistry · 1998 · 1.6K citations · Full text

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