Arthur J. Campbell

Predicting functional effects of missense variants in voltage-gated sodium and calcium channels

Henrike Heyne, David Báez-Nieto, Sumaiya Iqbal et al. · Science Translational Medicine · 2020 · 144 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants

Sumaiya Iqbal, Eduardo Pérez‐Palma, Jakob Berg Jespersen et al. · Proceedings of the National Academy of Sciences · 2020 · 126 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Biological concepts in human sodium channel epilepsies and their relevance in clinical practice

Andreas Brunklaus, Juanjiangmeng Du, Felix Steckler et al. · Epilepsia · 2020 · 98 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia

Florence F. Wagner, Lina Benajiba, Arthur J. Campbell et al. · Science Translational Medicine · 2018 · 96 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Rare De Novo Missense Variants in RNA Helicase DDX6 Cause Intellectual Disability and Dysmorphic Features and Lead to P-Body Defects and RNA Dysregulation

Chris Balak, Marianne Bénard, Élise Schaefer et al. · The American Journal of Human Genetics · 2019 · 86 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14