Priming of microglia with <scp>IFN</scp>‐γ impairs adult hippocampal neurogenesis and leads to depression‐like behaviors and cognitive defects

Jinqiang Zhang, Hui He, Yan Qiao, +8

Glia

Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway

Xue Jiang, Saini Yi, Qin Liu, +4

Journal of Neuroinflammation

IL-4 and IL-10 promotes phagocytic activity of microglia by up-regulation of TREM2

Saini Yi, Xue Jiang, Xiaofang Tang, +4

Cytotechnology

InflammationCytokineImmune RegulationImmunologyChronic Inflammation +5

The antidepressant effects of asperosaponin VI are mediated by the suppression of microglial activation and reduction of TLR4/NF-κB-induced IDO expression

Jinqiang Zhang, Saini Yi, Yahui Li, +5

Psychopharmacology

InflammationPsychoneuroimmunologyPsychiatryMicroglial ActivationTlr4/nf-κb-induced Ido Expression +10

Mouse Astrocytes Promote Microglial Ramification by Releasing TGF-β and Forming Glial Fibers

Jinqiang Zhang, Lijuan Zhang, Saini Yi, +5

Frontiers in Cellular Neuroscience

Glial BiologyBrain DevelopmentSynaptic SignalingCellular PhysiologySocial Sciences +18

Asperosaponin VI inhibits LPS-induced inflammatory response by activating PPAR-γ pathway in primary microglia

Jinqiang Zhang, Saini Yi, Chenghong Xiao, +5

Saudi Journal of Biological Sciences

Mapping the Plasticity of Morphology, Molecular Properties and Function in Mouse Primary Microglia

Xue Jiang, Hui He, Li Mo, +7

Frontiers in Cellular Neuroscience

Inflammatory Lung DiseaseInnate Immune SystemImmune RegulationImmunologyCell Death +25

Gut microbiota regulate stress resistance by influencing microglia-neuron interactions in the hippocampus

Haili He, Hui He, Li Mo, +7

Brain Behavior & Immunity - Health

The secretome of microglia induced by IL-4 of IFN-γ differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell by targeting the PI3K-Akt pathway

Xue Jiang, Saini Yi, Qin Liu, +1

Cytotechnology

Immune RegulationImmunologyCell DeathNeuroinflammationInflammation +14