Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities

Ya-Ming Meng, Xue Jiang, Xinbao Zhao, +10

Nature Communications

Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models

Liangping Su, Yitian Chen, Cheng Huang, +11

Science Translational Medicine

ApoptosisCell DeathCancer BiologyTumor BiologyOncology +14

Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway

Xue Jiang, Saini Yi, Qin Liu, +4

Journal of Neuroinflammation

Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation

Ying‐Zheng Zhao, Deli Zhuge, Meng‐Qi Tong, +8

Journal of Controlled Release

InflammationChronic Inflammatory DiseasesAnti-inflammatoryAutoimmune DiseaseImmunology +11

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

Xue Jiang, Yu Cheng, Caoling Xu, +11

Nature Communications

PHA-4/FoxA senses nucleolar stress to regulate lipid accumulation in Caenorhabditis elegans

Jieyu Wu, Xue Jiang, Yamei Li, +8

Nature Communications

Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

Eric L. Bradley, Somsankar Dasgupta, Xue Jiang, +6

PLoS ONE

ApoptosisCell DeathCancer BiologyCellular PhysiologyTumor Biology +19

A circular network of coregulated sphingolipids dictates lung cancer growth and progression

Qiong Meng, Xueting Hu, Xinbao Zhao, +10

EBioMedicine

Lipid transporter Spns2 promotes microglia pro‐inflammatory activation in response to amyloid‐beta peptide

Liansheng Zhong, Xue Jiang, Zhihui Zhu, +9

Glia

Spns2 KnockoutMicroglia InflammationImmunologySynaptic SignalingNeuroinflammation +17

Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes

Ji-Na Kong, Zhihui Zhu, Yutaka Itokazu, +11

Journal of Lipid Research