Steve Thibault

Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2

Athena Sudom, Santosh Talreja, Jean Danao et al. · Journal of Biological Chemistry · 2018 · 154 citations · Full text

Life Sciences, Molecular Genetics, Neuroscience +17

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)

Xiaoshan Min, Daniela Ungureanu, Sarah Sollid Maxwell et al. · Journal of Biological Chemistry · 2015 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo

Alykhan Motani, Zhulun Wang, Marion Conn et al. · Journal of Biological Chemistry · 2009 · 79 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3

Zhihong Li, Xianghong Wang, John Eksterowicz et al. · Journal of Medicinal Chemistry · 2014 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions

Sumedha Roy, Karen Fitzgerald, Almin Lalani et al. · Journal of Clinical Investigation · 2023 · 13 citations · Full text

Life Sciences, Immunology, Oncology +17