John Eksterowicz

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 296 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents

Jude Canon, Tao Osgood, Steven H. Olson et al. · Molecular Cancer Therapeutics · 2015 · 148 citations

Medicine, Oncology, Pharmacology +17

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)

Xiaoshan Min, Daniela Ungureanu, Sarah Sollid Maxwell et al. · Journal of Biological Chemistry · 2015 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Performance of 3D-Database Molecular Docking Studies into Homology Models

Connie Oshiro, Erin K. Bradley, John Eksterowicz et al. · Journal of Medicinal Chemistry · 2004 · 100 citations

Life Sciences, Bioinformatics, Medicinal Chemistry +17

Conformational preferences of the O-C-C-C unit in acyclic and cyclic systems. The exo-deoxoanomeric effect and related phenomena

K. N. Houk, John Eksterowicz, Yun Wu et al. · Journal of the American Chemical Society · 1993 · 86 citations

Natural Sciences, Chemistry, Crystal Structure +15