BNT162b vaccines protect rhesus macaques from SARS-CoV-2

Annette B. Vogel, Isis Kanevsky, Ye Che, +71

Nature

VaccinationBnt162b VaccinesVaccine DevelopmentVaccine TargetImmunology +2

Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening

Alexandra G. Orlandini von Niessen, Marco A. Poleganov, Corina Rechner, +10

Molecular Therapy

A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates

Annette B. Vogel, Isis Kanevsky, Ye Che, +58

VaccinationVaccine DevelopmentPrevents Lung InfectionVaccine ResearchImmunology +13

The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection

Christina M. Arieta, Yushu Joy Xie, Daniel Rothenberg, +24

Cell

Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference

Jan‐Niklas Tants, Stephanie Fesser, Thomas Kern, +11

Nucleic Acids Research

GeneticsMolecular BiologyMolecular GeneticsEpigeneticsDrosophila Loqs-pd/dcr-2 Complex +14

Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice

Alexander Muik, Bonny Gaby Lui, Maren Bacher, +28

Science Immunology

Humoral ResponseImmunologyImmunodominanceOmicron Ba.1Immunotherapy +15

BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2

Annette B. Vogel, Isis Kanevsky, Ye Che, +71

VaccinationBnt162b VaccinesVaccine DevelopmentVaccine TargetImmunology +13

Formation of dsRNA by-products during in vitro transcription can be reduced by using low steady-state levels of UTP

Thomas Ziegenhals, Ronja Frieling, Philipp Wolf, +7

Frontiers in Molecular Biosciences

Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones

Doris Berchtold, Stephanie Fesser, Gesine Bachmann, +9

Chromosome Research

Developmental BiologyNeuroanatomyThree-dimensional Cell CulturesChicken NeuronsDistinct Radial Zones +10

Transcription-dependent spatial arrangements of CFTR and conserved adjacent loci are not conserved in human and murine nuclei

Nicolas Sadoni, Bianca‐Sabrina Targosz, Andreas Englmann, +4

Chromosoma

ChromatinSystems BiologyMolecular PhysiologyTranscription-dependent Spatial ArrangementsAdjacent Loci +9