HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase

Lise Rivière, Laetitia Gérossier, Aurélie Ducroux, +6

Journal of Hepatology

Histone ModificationsChromatinTranscriptional RegulationChromatin RemodelingViral Hepatitis +10

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

Cheng Li, Wuqiang Zhan, Zhenlin Yang, +21

Cell

Sars-cov-2 VariantsBroad NeutralizationVaccine TargetImmunologyVirology +4

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, +34

Nature Microbiology

Pan-coronavirus ReactivityVaccine TargetHuman AntibodyNeutralization MechanismViral Pathogenesis +6

A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKɛ

Deguang Liang, Yuan Gao, Xianzhi Lin, +4

Cell Research

Viral LatencyViral PersistencePathogenesisImmunologyVirology +8

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA

Xianzhi Lin, Deguang Liang, Zhiheng He, +3

PLoS ONE

Viral ReplicationViral Orf50/rtaImmunologyPathologySeventeen Mirnas +16

Recombinant Covalently Closed Circular Hepatitis B Virus DNA Induces Prolonged Viral Persistence in Immunocompetent Mice

Zhihua Qi, Gaiyun Li, Hao Hu, +9

Journal of Virology

Viral ReplicationImmunologyHepatitis BMolecular BiologyHbv Cccdna +18

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

Chao Zhang, Yifan Wang, Yuanfei Zhu, +27

Nature Communications

Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5

Yunhua Liu, Rui Sun, Xianzhi Lin, +3

Journal of Virology

Altered Glycosylation Patterns Increase Immunogenicity of a Subunit Hepatitis C Virus Vaccine, Inducing Neutralizing Antibodies Which Confer Protection in Mice

Dapeng Li, Markus von Schaewen, Xuesong Wang, +8

Journal of Virology

Recombinant covalently closed circular DNA of hepatitis B virus induces long‐term viral persistence with chronic hepatitis in a mouse model

Gaiyun Li, Yuanfei Zhu, Dianhui Shao, +6

Hepatology