A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

Yunkai Zhu, Fei Feng, Gaowei Hu, +17

Nature Communications

Global SpreadOff-target EffectGeneticsPathogenesisViral Pathogenesis +13

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

Yinghui Liu, Gaowei Hu, Yuyan Wang, +22

Proceedings of the National Academy of Sciences

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

Cheng Li, Wuqiang Zhan, Zhenlin Yang, +21

Cell

Sars-cov-2 VariantsBroad NeutralizationVaccine TargetImmunologyVirology +4

Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2

Yunqing Gu, Jun Cao, Xinyu Zhang, +23

Cell Research

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, +34

Nature Microbiology

Pan-coronavirus ReactivityVaccine TargetHuman AntibodyNeutralization MechanismViral Pathogenesis +6

Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2

Yinghui Liu, Gaowei Hu, Yuyan Wang, +14

Genetic AnalysisViral EvolutionEmerging Infectious DiseasesVirus EntryViral Pathogenesis +13

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

Chao Zhang, Yifan Wang, Yuanfei Zhu, +27

Nature Communications

Recombinant covalently closed circular DNA of hepatitis B virus induces long‐term viral persistence with chronic hepatitis in a mouse model

Gaiyun Li, Yuanfei Zhu, Dianhui Shao, +6

Hepatology

Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection

Jinkai Zang, Yuanfei Zhu, Yu Zhou, +16

Cell Discovery

Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2

Chenjian Gu, Yang Wu, Huimin Guo, +14

Science Bulletin

Protoporphyrin IxMedicinePathogenesisImmunologyViral Pathogenesis +8