Identification of RNF213 as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development

Wanyang Liu, Daisuke Morito, Seiji Takashima, +20

PLoS ONE

Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients

Toshiaki Hitomi, Toshiyuki Habu, Hatasu Kobayashi, +17

Biochemical and Biophysical Research Communications

Induced Pluripotent Stem CellAngiogenesisMedicineEndothelial DysfunctionAngiogenic Activity +8

The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality

Toshiaki Hitomi, Toshiyuki Habu, Hatasu Kobayashi, +17

Biochemical and Biophysical Research Communications

Disease MechanismGenetic DisorderGeneticsPathogenesisPathology +6

A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians

Wanyang Liu, Hirokuni Hashikata, Kayoko Inoue, +16

Environmental Health and Preventive Medicine

Bridging veins and veins of the brainstem in microvascular decompression surgery for trigeminal neuralgia and hemifacial spasm

Hiroki Toda, Koichi Iwasaki, Naoya Yoshimoto, +4

Neurosurgical FOCUS

Confirmation of an Association of Single-Nucleotide Polymorphism rs1333040 on 9p21 With Familial and Sporadic Intracranial Aneurysms in Japanese Patients

Hirokuni Hashikata, Wanyang Liu, Kayoko Inoue, +9

Stroke

Rapid Progression of Unilateral Moyamoya Disease in a Patient with a Family History and an <b><i>RNF213</i></b> Risk Variant

Yohei Mineharu, Yasushi Takagi, Jun Takahashi, +6

Cerebrovascular Diseases

Usefulness of a large automated health records database in pharmacoepidemiology

Hirokuni Hashikata, Kouji H. Harada, Tatsuo Kagimura, +2

Environmental Health and Preventive Medicine

Autologous clavicle bone graft for anterior cervical discectomy and fusion with titanium interbody cage

Koichi Iwasaki, Taichi Ikedo, Hirokuni Hashikata, +1

Journal of Neurosurgery Spine

Intervertebral DiscAnterior Cervical DiscectomySurgeryTitanium Interbody CageOrthopaedic Surgery +15

Intramedullary spinal cord abscess and subsequent granuloma formation: a rare complication of vertebral osteomyelitis detected by diffusion-weighted magnetic resonance imaging

Noriyoshi Takebe, Koichi Iwasaki, Hirokuni Hashikata, +1

Neurosurgical FOCUS

Vertebral OsteomyelitisPathologySurgeryThoracic SpineCauda Equina +14