James J. Kohler

Tenofovir renal toxicity targets mitochondria of renal proximal tubules

James J. Kohler, Seyed Hamzeh Hosseini, Amy Hoying‐Brandt et al. · Laboratory Investigation · 2009 · 190 citations · Full text

Urology, Medicine, Pathology +6

Tenofovir renal proximal tubular toxicity is regulated By OAT1 and MRP4 transporters

James J. Kohler, Seyed Hamzeh Hosseini, Elgin Green et al. · Laboratory Investigation · 2011 · 156 citations · Full text

Molecular Pharmacology, Urology, Renal Function +8

Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ

William Lewis, Brian J. Day, James J. Kohler et al. · Laboratory Investigation · 2007 · 121 citations · Full text

Cardiomyopathy, Transgenic Cardiac, Mitochondrial Function +10

Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol γ hypothesis

William Lewis, James J. Kohler, Seyed Hamzeh Hosseini et al. · AIDS · 2006 · 114 citations · Full text

HIV-1 Activates Macrophages Independent of Toll-Like Receptors

Joseph N. Brown, James J. Kohler, Carter R. Coberley et al. · PLoS ONE · 2008 · 94 citations · Full text