Concepedia

Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ

William Lewis, Brian J. Day, James J. Kohler, Seyed H. Hosseini, Sherine S.L. Chan, Elgin C Green, Chad P. Haase, Erin S. Keebaugh, Robert C. Long, Tomika Ludaway,

Laboratory Investigation · 2007 · 121 citations · 41 references

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41

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.2K citations

, , +17

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

Yibing Li, Ting‐Ting Huang, Elaine J. Carlson et al. · Nature Genetics · 1995 · 1.8K citations

, , +10

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

Christoph Richter, J W Park, B N Ames · Proceedings of the National Academy of Sciences · 1988 · 1.7K citations · Full text

, , +17

Thymidine Phosphorylase Gene Mutations in MNGIE, a Human Mitochondrial Disorder

Ichizo Nishino, Antonella Spinazzola, Michio Hirano · Science · 1999 · 900 citations

, , +17