An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Yanchun Peng, Suet Ling Felce, Danning Dong, +62

Nature Immunology

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

Moses Moustakim, Thomas Christott, Octovia Monteiro, +23

Angewandte Chemie International Edition

Molecular BiologyChemistryCancer BiologyEpigeneticsAnalytical Instrumentation +16

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas

P. Brown, Kah Keng Wong, Suet Ling Felce, +8

Leukemia

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9

Thomas Christott, James M. Bennett, Carmen Coxon, +10

SLAS DISCOVERY

CRISPR/Cas9-Mediated Foxp1 Silencing Restores Immune Surveillance in an Immunocompetent A20 Lymphoma Model

Suet Ling Felce, Amanda P. Anderson, Shaun Maguire, +5

Frontiers in Oncology

Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells

Chiara Cassioli, Štefan Bálint, Ewoud B. Compeer, +11

Frontiers in Cell and Developmental Biology

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells

Philip J. Brown, D. M. Gascoyne, Linden Lyne, +9

Haematologica

HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

Hongbing Yang, Hong Sun, Simon Brackenridge, +21

Science Immunology

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection

Martina Milighetti, Yanchun Peng, Cedric Tan, +31

iScience

Viral DiagnosticsAdaptive Immune SystemImmunologyViral PathogenesisTcr Cdr3s +14

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Dannielle Wellington, Zixi Yin, Zhanru Yu, +13

Heliyon