James M. Bennett

An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

David J. Haydon, Neil R. Stokes, Rebecca Ure et al. · Science · 2008 · 436 citations · Full text

Selective Anti-staphylococcal Activity, Pharmacotherapy, Antimicrobial Chemotherapy +17

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Efrat Resnick, A.R. Bradley, Jinrui Gan et al. · Journal of the American Chemical Society · 2019 · 323 citations · Full text

Chemical Biology, Selective Probes, Biochemistry +15

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

M. Schuller, G.J. Correy, Stefan Gahbauer et al. · Science Advances · 2021 · 198 citations · Full text

Engineering, Nsp3 Macrodomain, Molecular Biology +16

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

Peter G. K. Clark, Lucas Campos Curcino Vieira, C. Tallant et al. · Angewandte Chemie International Edition · 2015 · 162 citations · Full text

Lead Scaffold, Molecular Pharmacology, Medicinal Chemistry +15

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

Melissa L. Boby, D. Fearon, Matteo P. Ferla et al. · Science · 2023 · 158 citations · Full text