Ryosuke Hibino

Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor

Kenichi Iwai, Tadahiro Nambu, Ryo Dairiki et al. · Science Advances · 2019 · 70 citations · Full text

Medicine, Oncology, Pharmacology +6

T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice

Satoru Matsuda, Rina Baba, Hideyuki Oki et al. · Neuropsychopharmacology · 2018 · 45 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +4

Antitumor Activity and Pharmacodynamic Biomarkers of a Novel and Orally Available Small-Molecule Antagonist of Inhibitor of Apoptosis Proteins

Hiroyuki Sumi, Masato Yabuki, Kenichi Iwai et al. · Molecular Cancer Therapeutics · 2012 · 13 citations

Life Sciences, Oncology, Pharmacology +17

An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924)

Hiroyuki Sumi, Masakazu Inazuka, Megumi Morimoto et al. · Biochemical and Biophysical Research Communications · 2016 · 10 citations

Life Sciences, Oncology, Pharmacology +16