Catherine Huntington

Oxidised IL-33 drives COPD epithelial pathogenesis<i>via</i>ST2-independent RAGE/EGFR signalling complex

Sam Strickson, Kirsty F. Houslay, Victor Augusti Negri et al. · European Respiratory Journal · 2023 · 71 citations · Full text

Affinity maturation of a novel antagonistic human monoclonal antibody with a long V_HCDR3 targeting the Class A GPCR formyl-peptide receptor 1

Julie A. Douthwaite, Sudharsan Sridharan, Catherine Huntington et al. · mAbs · 2014 · 39 citations · Full text

Peptide Engineering, Immunology, Fpro0165 Fab +16

Haplosaurus computes protein haplotypes for use in precision drug design

William Spooner, William McLaren, Timothy Slidel et al. · Nature Communications · 2018 · 32 citations · Full text

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

Julie A. Douthwaite, Jacques Moisan, Cyril V. Privezentzev et al. · The Journal of Immunology · 2016 · 20 citations · Full text

Use of the Site-Specific Retargeting Jump-In Platform Cell Line to Support Biologic Drug Discovery

Robin Butler, David C. Hornigold, Ling Huang et al. · SLAS DISCOVERY · 2014 · 16 citations · Full text

Engineering, Drug Discovery Projects, Molecular Biological Method +15