Xavier M. Anguela - Concepedia

Author

Xavier M. Anguela

Children's Hospital of Philadelphia ORCID

Also Known As

X M Anguela, X. Anguela, X.M. Anguela, Xavier Anguela, Xavier M Anguela, Xavier M. Anguela

Publications

4.1K

Citations

H-Index

Concepts

All Affiliations

Children's Hospital of Philadelphia Spark Therapeutics (United States)University of Pennsylvania Howard Hughes Medical Institute Universitat Autònoma de Barcelona

About

Xavier M. Anguela is an author at Children's Hospital of Philadelphia specializing in medicine, cell biology, and immunology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	1.2K
2	Engineering	2	2	572
3	Health Sciences	1	1	60
4	Applied Physiology	1	1	60
5	Biomedical Engineering	1	1	60

Xavier M. Anguela

Publications

3.5K

Citations

H-Index

Page 1

	Year	Citations
Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant Lindsey A. George, Spencer K. Sullivan, Adam Giermasz, New England Journal of Medicine	2017	736
In vivo genome editing restores haemostasis in a mouse model of haemophilia Hojun Li, Virginia Haurigot, Yannick Doyon, Nature Vivo GenomeKnockout MouseEngineeringGenome SurgeryGenetics	2011	540
Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys Federico Mingozzi, Xavier M. Anguela, Giulia Pavani, Science Translational Medicine	2013	335
In vivo genome editing of the albumin locus as a platform for protein replacement therapy Rajiv P. Sharma, Xavier M. Anguela, Yannick Doyon, Blood	2015	295
IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies Christian Leborgne, Elena Barbon, J M Alexander, Nature Medicine Vivo Gene TherapyAutoimmune DiseaseIgg-cleaving Endopeptidase EnablesImmunologyAutoimmunity	2020	295
High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency Eduard Ayuso, Federico Mingozzi, Joel Montané, Gene Therapy Synthetic VirologyGeneticsTransduction EfficiencyGenetic EngineeringVirology	2009	271
Multiyear Factor VIII Expression after AAV Gene Transfer for Hemophilia A Lindsey A. George, Paul E. Monahan, M. Elaine Eyster, New England Journal of Medicine	2021	234
Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B Lindsey A. George, Margaret V. Ragni, John E.J. Rasko, Molecular Therapy	2020	198
Robust ZFN-mediated genome editing in adult hemophilic mice Xavier M. Anguela, Rajiv P. Sharma, Yannick Doyon, Blood	2013	172
Reversal of Type 1 Diabetes by Engineering a Glucose Sensor in Skeletal Muscle Alex Mas, Joel Montané, Xavier M. Anguela, Diabetes Glucose HomeostasisGlucose SensorBiomedical EngineeringGlucose ToleranceArtificial Pancreas	2006	60

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