Hyang Yeon Lee

Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis

Evijola Llabani, Robert W. Hicklin, Hyang Yeon Lee et al. · Nature Chemistry · 2019 · 221 citations

Diverse Compounds, Biochemistry, Pleuromutilin Lead +9

Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens

Erica N. Parker, Bryon Drown, Emily J. Geddes et al. · Nature Microbiology · 2019 · 125 citations · Full text

Permeation Rules, Fabi Inhibitor, Health Sciences +13

A Gram-negative-selective antibiotic that spares the gut microbiome

Kristen A. Muñoz, Rebecca J. Ulrich, Archit Vasan et al. · Nature · 2024 · 107 citations · Full text

Gram-negative Bacteriology, Dysbiosis, Antibiotics +7

Gram-Negative Antibiotic Active Through Inhibition of an Essential Riboswitch

Stephen E. Motika, Rebecca J. Ulrich, Emily J. Geddes et al. · Journal of the American Chemical Society · 2020 · 77 citations · Full text

An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with <i>In Vivo</i> Efficacy against Drug-Resistant Gram-Negative Infections

Erica N. Parker, Brett N. Cain, Behnoush Hajian et al. · ACS Central Science · 2022 · 71 citations · Full text