Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

Alexander S. Pym, Priscille Brodin, Laleh Majlessi, +7

Nature Medicine

Medical MicrobiologyPulmonary TuberculosisPathogenesisImmunologyTuberculosis Prevention +5

Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials

Ainhoa Arbués, Jesús Gonzalo‐Asensio, Dessislava Marinova, +13

Vaccine

VaccinationPulmonary TuberculosisVaccine DevelopmentVaccine ResearchVaccine Target +9

NMR and Pattern Recognition Studies on the Time-Related Metabolic Effects of α-Naphthylisothiocyanate on Liver, Urine, and Plasma in the Rat:  An Integrative Metabonomic Approach

Nigel J. Waters, Elaine Holmes, Ann Williams, +3

Chemical Research in Toxicology

Metabolomic ProfilingMas Nmr TechniquesToxicological MechanismTime-related Metabolic EffectsMetabolic Pathway Analysis +21

Protective Effect of a Tuberculosis Subunit Vaccine Based on a Fusion of Antigen 85B and ESAT-6 in the Aerosol Guinea Pig Model

Anja Weinreich Olsen, Ann Williams, Limei Meng Okkels, +2

Infection and Immunity

Microbial PathogensTuberculosis PreventionImmunologyImmunodominanceAntigen Processing +19

Passive protection with immunoglobulin A antibodies against tuberculous early infection of the lungs

Ann Williams, Rajko Reljić, Irene Naylor, +6

Immunology

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

Ann Williams, Graham Hatch, Simon Clark, +30

Tuberculosis

VaccinationPulmonary TuberculosisVaccine DevelopmentVaccine TargetTuberculosis Prevention +5

Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations

S. Sharpe, Andrew White, Charlotte Sarfas, +10

Tuberculosis

Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases

Naomi F. Walker, Simon Clark, Tolu Oni, +14

American Journal of Respiratory and Critical Care Medicine

Role of IgA in the defense against respiratory infections

Ariane Rodrı́guez, Anna Tjärnlund, Juraj Ivanji, +6

Vaccine

AsthmaLung InflammationImmunologyRespiratory InfectionInfectious Respiratory Disease +3

The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis

Joanna Bacon, Brian W. James, Lorenz Wernisch, +8

Tuberculosis

Medical MicrobiologyPulmonary TuberculosisOxygen AvailabilityNatural SciencesPathogenesis +10