T.M. Gloster

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

T.M. Gloster, Wesley F. Zandberg, Julia Heinonen et al. · Nature Chemical Biology · 2011 · 320 citations

Life Sciences, Biochemistry, Molecular Biology +14

An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Januka S. Athukoralage, S.A. McMahon, Changyi Zhang et al. · Nature · 2020 · 211 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +11

The Mechanisms by Which Family 10 Glycoside Hydrolases Bind Decorated Substrates

G. Pell, Edward J. Taylor, T.M. Gloster et al. · Journal of Biological Chemistry · 2004 · 181 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Fiona Cuskin, J.E. Flint, T.M. Gloster et al. · Proceedings of the National Academy of Sciences · 2012 · 170 citations · Full text

Life Sciences, Biochemistry, Biocatalysis +16

Iminosugar Glycosidase Inhibitors:  Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to β-Glucosidases

David L. Zechel, A.B. Boraston, T.M. Gloster et al. · Journal of the American Chemical Society · 2003 · 169 citations

Life Sciences, Biochemistry, Medicinal Chemistry +15