T.M. Gloster

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

T.M. Gloster, Wesley F. Zandberg, Julia Heinonen et al. · Nature Chemical Biology · 2011 · 319 citations

Biosynthesis, Signal Transduction, Cellular Enzymology +11

An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Januka S. Athukoralage, S.A. McMahon, Changyi Zhang et al. · Nature · 2020 · 206 citations · Full text

Engineering, Pathogenesis, Immunology +10

The Mechanisms by Which Family 10 Glycoside Hydrolases Bind Decorated Substrates

G. Pell, Edward J. Taylor, T.M. Gloster et al. · Journal of Biological Chemistry · 2004 · 179 citations · Full text

Iminosugar Glycosidase Inhibitors:  Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to β-Glucosidases

David L. Zechel, A.B. Boraston, T.M. Gloster et al. · Journal of the American Chemical Society · 2003 · 168 citations

Transition-state Mimics, Iminosugar Glycosidase Inhibitors, Favorable Enthalpy +18

How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Fiona Cuskin, J.E. Flint, T.M. Gloster et al. · Proceedings of the National Academy of Sciences · 2012 · 167 citations · Full text