New advances in DPYD genotype and risk of severe toxicity under capecitabine

Marie-Christine Étienne-Grimaldi, Jean-Christophe Boyer, Christophe Béroud, +30

PLoS ONE

Sudden Death Related to Toxicity in a Patient on Capecitabine and Irinotecan Plus Bevacizumab Intake: Pharmacogenetic Implications

Laëtitia Dahan, Joseph Ciccolini, Alexandre Evrard, +9

Journal of Clinical Oncology

Effect of Single Nucleotide Polymorphisms in the Xenobiotic-sensing Receptors NR1I2 and NR1I3 on the Pharmacokinetics and Toxicity of Irinotecan in Colorectal Cancer Patients

Litaty Mbatchi, Jacques Robert, Marc Ychou, +5

Clinical Pharmacokinetics

Health SciencesSingle Nucleotide PolymorphismsMedicineOncogenic AgentPharmacology +8

PXR Modulates the Prostate Cancer Cell Response to Afatinib by Regulating the Expression of the Monocarboxylate Transporter SLC16A1

Alice Matheux, Matthieu Gassiot, Gaëlle Fromont, +13

Cancers

Molecular PharmacologyPerineural InvasionMedicinePharmacologyKinase Inhibitors +13

Polymorphisms in <i>Slco1B3</i> and <i>Nr1I2</i> as Genetic Determinants of Hematotoxicity of Carboplatin and Paclitaxel Combination

Litaty Mbatchi, Antonin Schmitt, Fabienne Thomas, +8

Pharmacogenomics

Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer

Litaty Mbatchi, Matthieu Gassiot, Philippe Pourquier, +6

Cancer Chemotherapy and Pharmacology

UrologyGenitourinary CancerTemsirolimus PharmacokineticsMedicineCancer Genetics +4

Caspofungin Population Pharmacokinetic Analysis in Plasma and Peritoneal Fluid in Septic Patients with Intra-Abdominal Infections: A Prospective Cohort Study

Nicolas Garbez, Litaty Mbatchi, Steven C. Wallis, +5

Clinical Pharmacokinetics

Intra-abdominal InfectionsSeptic PatientsSepsisClinical InfectionSepsis Phenotyping +2

Prospective Cohort Study of Micafungin Population Pharmacokinetic Analysis in Plasma and Peritoneal Fluid in Septic Patients with Intra-abdominal Infections

Nicolas Garbez, Litaty Mbatchi, Steven C. Wallis, +5

Antimicrobial Agents and Chemotherapy

Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug–Drug Interactions Are the Usual Suspects

Fanny Leenhardt, Frédéric Fiteni, Ludovic Gauthier, +13

Pharmaceutics

Breast OncologyPalbociclib PlasmaUsual SuspectsPharmacotherapyDrug–drug Interactions +19

Liquid chromatography–tandem mass spectrometric assay for the quantification of CDK4/6 inhibitors in human plasma in a clinical context of drug-drug interaction

Fanny Leenhardt, Matthieu Gracia, Catherine Perrin, +10

Journal of Pharmaceutical and Biomedical Analysis

Therapeutic Drug MonitoringPharmacokinetic ModelingMedicineBioanalysisMass Spectrometry +12