Targeting the human malaria parasite Plasmodium falciparum: In vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Human Malaria Parasites in Continuous Culture

William Trager, James B. Jensen · Science · 1976 · 8K citations

Life Sciences, Biology, Infectious Diseases +15

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

Bruce N. Ames, Frank D. Lee, William E. Durston · Proceedings of the National Academy of Sciences · 1973 · 1.5K citations · Full text

Life Sciences, Genetics, Microbiology +12

Chemical genetics of Plasmodium falciparum

W. Armand Guiguemde, Anang A. Shelat, David C. Bouck et al. · Nature · 2010 · 568 citations · Full text

Life Sciences, Genetics, Molecular Biology +7

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

Cristina Rodríguez‐Antona, M. Teresa Donato, Alan R. Boobis et al. · Xenobiotica · 2002 · 417 citations

Medicine, Biochemistry, Molecular Biology +12