Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks

Alexandra Bour, Jeannette Grootendorst, Elise Vogel, +6

Behavioural Brain Research

Spatial Memory TasksCognitive ScienceAlzheimer's DiseaseAgingBrain Function +9

Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75‐saporin in mice

Pierre‐Henri Moreau, Brigitte Cosquer, Hélène Jeltsch‐David, +2

Hippocampus

Synaptic TransmissionNeurotransmitterSynaptic SignalingSocial SciencesNeuroinflammation +20

A single-shot Lassa vaccine induces long-term immunity and protects cynomolgus monkeys against heterologous strains

Mathieu Mateo, Stéphanie Reynard, Alexandra Journeaux, +20

Science Translational Medicine

VaccinationVaccine DevelopmentCynomolgus MonkeysHeterologous StrainsNeurovirology +13

Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer’s disease and frontotemporal lobar degeneration

Valeria Melis, Claudia Zabke, Karsten Stamer, +18

Cellular and Molecular Life Sciences

Lesions of the anterior thalamic nuclei and intralaminar thalamic nuclei: place and visual discrimination learning in the water maze

Pierre‐Henri Moreau, Yanina Tsenkina, Lucas Lecourtier, +5

Brain Structure and Function

Cognitive ScienceWater MazeNeural MechanismDevelopmental Cognitive NeuroscienceNeuroanatomy +8

High-efficiency base editing in the retina in primates and human tissues

Alissa Muller, Jack M. Sullivan, Wibke Schwarzer, +45

Nature Medicine

Attenuated behavioural responses to acute and chronic cocaine in GASP‐1‐deficient mice

Julien Boeuf, José Trigo, Pierre‐Henri Moreau, +7

European Journal of Neuroscience

PsychopharmacologyCocaineGasp‐1‐deficient MiceSocial SciencesProtein 1 +20

A MOPEVAC multivalent vaccine induces sterile protection against New World arenaviruses in non-human primates

Stéphanie Reynard, Xavier Carnec, Caroline Picard, +22

Nature Microbiology

VaccinationVaccine DevelopmentNew WorldImmunologyVirology +5

ApoE4 confers better spatial memory than apoE3 in young adult hAPP-Yac/apoE-TR mice

Pierre‐Henri Moreau, Jean-Bastien Bott, Celina Zerbinatti, +4

Behavioural Brain Research

NeuropsychologyBrain DevelopmentDevelopmental Cognitive NeuroscienceBrain HealthBehavioral Neuroscience +9

High-efficiency base editing for Stargardt disease in mice, non-human primates, and human retina tissue

Alissa Muller, Jack M. Sullivan, Wibke Schwarzer, +35

Ocular DiseaseIn Vivo Gene TherapyAbstract Stargardt DiseaseOptogeneticsRetina +16