Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

CNS Synaptogenesis Promoted by Glia-Derived Cholesterol

Daniela H. Mauch, Karl Nägler, Stefan Schumacher et al. · Science · 2001 · 1.7K citations

Life Sciences, Neurobiology, Neuroscience +17

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1993 · 1.5K citations · Full text

Life Sciences, Genetics, Neuroscience +17

Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions

G. William Rebeck, Joell S. Reiter, Dudley K. Strickland et al. · Neuron · 1993 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +17

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

Patrick M. Sullivan, Hafid Mezdour, Yasuaki Aratani et al. · Journal of Biological Chemistry · 1997 · 597 citations · Full text

Life Sciences, Biochemistry, Genetics +15