Jürgen Grünberg

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Taisuke Tomita, Kei Maruyama, Takaomi C. Saido et al. · Proceedings of the National Academy of Sciences · 1997 · 385 citations

Life Sciences, Genetics, Molecular Biology +16

Site‐Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase

Simone Jeger, Kurt Zimmermann, Alain Blanc et al. · Angewandte Chemie International Edition · 2010 · 330 citations

Pharmacy, Oncology, Pharmacology +17

The Proteolytic Fragments of the Alzheimer's Disease-associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex

Anja Capell, Jürgen Grünberg, Brigitte Pesold et al. · Journal of Biological Chemistry · 1998 · 326 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

The Alzheimer’s Disease-Associated Presenilins Are Differentially Phosphorylated Proteins Located Predominantly within the Endoplasmic Reticulum

Jochen Walter, Anja Capell, Jürgen Grünberg et al. · Molecular Medicine · 1996 · 228 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +13

Human presenilin‐1, but not familial Alzheimer’s disease (FAD) mutants, facilitate <i>Caenorhabditis elegans</i> Notch signalling independently of proteolytic processing

Ralf Baumeister, Uwe Leimer, I. Zweckbronner et al. · Genes and Function · 1997 · 203 citations

Life Sciences, Genetics, Molecular Genetics +16