P. Dostert

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies

Makoto Naoi, Wakako Maruyama, P. Dostert et al. · Brain Research · 1996 · 136 citations

Behavioral Studies, Medicine, Behavioral Pharmacology +9

A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol

Makoto Naoi, Wakako Maruyama, P. Dostert et al. · Neuroscience Letters · 1996 · 128 citations

Bioorganic Chemistry, Biochemistry, Medicine +11

Differential Changes in Superoxide Dismutase Activity in Brain and Liver of Old Rats and Mice

H. Cao Danh, M. Strolin Benedetti, P. Dostert · Journal of Neurochemistry · 1983 · 105 citations

Lipid Peroxidation, Whole Brain, Redox Biology +17

A dopaminergic neurotoxin, (<i>R</i>)‐N‐methylsalsolinol, increases in parkinsonian cerebrospinal fluid

Wakako Maruyama, Takashi Abe, Hideo Tohgi et al. · Annals of Neurology · 1996 · 103 citations

A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain

Wakako Maruyama, Gen Sobue, Kazuo Matsubara et al. · Neuroscience Letters · 1997 · 101 citations

Oxidation Product, Neurophysiology, Neuroanatomy +11