Regulation of Obesity-Related Insulin Resistance with Gut Anti-inflammatory Agents

Helen Luck, Sue Tsai, Jason Chung, +22

Cell Metabolism

InflammationMetabolic SyndromeObesityInsulin ResistanceMedicine +6

Targeting immune–fibroblast cell communication in heart failure

Junedh Amrute, Xin Luo, Vinay Penna, +32

Nature

InflammationCardiomyopathyHeart FailureImmune RegulationImmunology +3

DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice

Sally Yu Shi, Shun-Yan Lu, Tharini Sivasubramaniyam, +12

Nature Communications

In Vivo Role of Focal Adhesion Kinase in Regulating Pancreatic β-Cell Mass and Function Through Insulin Signaling, Actin Dynamics, and Granule Trafficking

Erica P. Cai, Marina Casimir, Stephanie A. Schroer, +10

Diabetes

Cell AdhesionCytoskeletonGranule TraffickingCellular PhysiologyInsulin Signaling +20

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance

Xavier S. Revelo, Magar Ghazarian, Melissa Hui Yen Chng, +21

Cell Reports

ImmunologyFatty Liver DiseaseInsulin SignalingInflammationMetabolic Syndrome +14

Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance

Sally Yu Shi, Rubén García-Martín, Robin E. Duncan, +15

Journal of Biological Chemistry

FAK signalling controls insulin sensitivity through regulation of adipocyte survival

Cynthia T. Luk, Sally Yu Shi, Erica P. Cai, +6

Nature Communications

Perforin Is a Novel Immune Regulator of Obesity-Related Insulin Resistance

Xavier S. Revelo, Sue Tsai, Helena Lei, +11

Diabetes

Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing

Sally Yu Shi, Cynthia T. Luk, Jara J. Brunt, +4

Diabetologia

ObesityMetabolic SyndromeLipid SynthesisMetabolic DisorderMedicine +11

Genetic Variation of DKK3 May Modify Renal Disease Severity in ADPKD

Sally Yu Shi, Sean Senthilnathan, Julie Yu, +23

Journal of the American Society of Nephrology