Robert H. Field

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

Robert H. Field, Suzanne Campion, Colleen Warren et al. · Brain Behavior and Immunity · 2010 · 207 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Prior Pathology in the Basal Forebrain Cholinergic System Predisposes to Inflammation-Induced Working Memory Deficits: Reconciling Inflammatory and Cholinergic Hypotheses of Delirium

Robert H. Field, Anna Gossen, Colm Cunningham · Journal of Neuroscience · 2012 · 167 citations · Full text

Life Sciences, Neurology, Neuroscience +15

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

Arshed Nazmi, Robert H. Field, Éadaoin W. Griffin et al. · Glia · 2019 · 137 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrP^Sc, even upon LPS stimulation

Martina M. Hughes, Robert H. Field, V. Hugh Perry et al. · Glia · 2010 · 93 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

<scp>DNA</scp> sensors are expressed in astrocytes and microglia <i>in vitro</i> and are upregulated during gliosis in neurodegenerative disease

Donal J Cox, Robert H. Field, David G. Williams et al. · Glia · 2015 · 79 citations · Full text

Life Sciences, Immunology, Neuroscience +17