Martina M. Hughes

Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder

Thomas Frodl, Angela Carballedo, Martina M. Hughes et al. · Translational Psychiatry · 2012 · 175 citations · Full text

Veterinary Medicine, Neuroscience, Psychiatry +17

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain

Ksenia Kurbatskaya, Emma Claire Phillips, Cara L. Croft et al. · Acta Neuropathologica Communications · 2016 · 145 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation

Martina M. Hughes, Angela Carballedo, Declan M. McLoughlin et al. · Brain Behavior and Immunity · 2012 · 105 citations

Medicine, Pharmacology, Psychiatry +11

C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy

Maria Pertl, David Hevey, Noreen T. Boyle et al. · Brain Behavior and Immunity · 2013 · 95 citations

Medicine, Oncology, Breast Oncology +13

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrP^Sc, even upon LPS stimulation

Martina M. Hughes, Robert H. Field, V. Hugh Perry et al. · Glia · 2010 · 93 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17