Thomas Hollis

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

Min Ae Lee‐Kirsch, Maolian Gong, Dipanjan Chowdhury et al. · Nature Genetics · 2007 · 716 citations

Autoimmune Disease, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus Treatment +11

Heterozygous Mutations in TREX1 Cause Familial Chilblain Lupus and Dominant Aicardi-Goutières Syndrome

Gillian Rice, William G. Newman, John Dean et al. · The American Journal of Human Genetics · 2007 · 403 citations · Full text

Mendelian Disorder, Autoimmune Disease, Genetic Disorder +10

Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase

Rebecca D. Powell, Paul J. Holland, Thomas Hollis et al. · Journal of Biological Chemistry · 2011 · 331 citations · Full text

DNA bending and a flip-out mechanism for base excision by the helix–hairpin–helix DNA glycosylase, Escherichia coli AlkA

Thomas Hollis, Yoshitaka Ichikawa, Tom Ellenberger · The EMBO Journal · 2000 · 216 citations · Full text

Base Excision, Nucleic Acid Chemistry, Dna Bending +9

A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

Min Ae Lee‐Kirsch, Dipanjan Chowdhury, Scott Harvey et al. · Journal of Molecular Medicine · 2007 · 216 citations

Immunogenetics, Autoimmune Disease, Disease Mechanism +11