Alexander Oster

Design, Synthesis, Biological Evaluation and Pharmacokinetics of Bis(hydroxyphenyl) substituted Azoles, Thiophenes, Benzenes, and Aza-Benzenes as Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Ruth Werth et al. · Journal of Medicinal Chemistry · 2008 · 107 citations · Full text

New Insights into the SAR and Binding Modes of Bis(hydroxyphenyl)thiophenes and -benzenes: Influence of Additional Substituents on 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitory Activity and Selectivity

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Matthias Negri et al. · Journal of Medicinal Chemistry · 2009 · 75 citations · Full text

Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) for the treatment of estrogen-dependent diseases

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Patricia Kruchten et al. · Bioorganic & Medicinal Chemistry · 2008 · 65 citations · Full text

Medicinal Chemistry, Estrogen-dependent Diseases, Biochemistry +11

Selective inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17βHSD1) reduces estrogen responsive cell growth of T47-D breast cancer cells

Patricia Kruchten, Ruth Werth, Emmanuel Bey et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 38 citations

Selective Inhibition, Breast Oncology, Responsive Cell Growth +8

Bicyclic Substituted Hydroxyphenylmethanones as Novel Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) for the Treatment of Estrogen-Dependent Diseases

Alexander Oster, Stefan Hinsberger, Ruth Werth et al. · Journal of Medicinal Chemistry · 2010 · 37 citations · Full text

Chemoprevention Strategy, Bicyclic Substituted Hydroxyphenylmethanones, Chemical Biology +19