Klára Tótpál

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL

Klaus W. Wagner, Elizabeth A. Punnoose, Thomas Januario et al. · Nature Medicine · 2007 · 603 citations

Life Sciences, Cell Biology, Oncology +16

Tumor-cell resistance to death receptor–induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax

Heidi Leblanc, David A. Lawrence, Eugene Varfolomeev et al. · Nature Medicine · 2002 · 506 citations

Life Sciences, Cell Biology, Oncology +15

Identification of multiple sources of charge heterogeneity in a recombinant antibody

Reed J. Harris, Bruce Kabakoff, Frank Macchi et al. · Journal of Chromatography B Biomedical Sciences and Applications · 2001 · 503 citations

Pharmacy, Biochemistry, Molecular Biology +16

PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer

Soyoung Oh, Dai-Chen Wu, Jeanne Cheung et al. · Nature Cancer · 2020 · 459 citations

Life Sciences, Immunology, Oncology +17

Preclinical Studies to Predict the Disposition of Apo2L/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Humans: Characterization of in Vivo Efficacy, Pharmacokinetics, and Safety

Sean K. Kelley, Louise A. Harris, David Xie et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 443 citations

Life Sciences, Oncology, Pharmacology +17