Aniruddha J. Deshpande

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia

Chun‐Wei Chen, Richard P. Koche, Amit Sinha et al. · Nature Medicine · 2015 · 248 citations · Full text

Hematological Malignancy, Tumor Biology, Chromatin +11

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice

Christina Schessl, Vijay P.S. Rawat, Monica Cusan et al. · Journal of Clinical Investigation · 2005 · 240 citations · Full text

Hematological Malignancy, Systems Biology, Signal Transduction +13

Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in <i>NPM1</i> Mutant Leukemia

Michael W.M. Kühn, E Song, Zhaohui Feng et al. · Cancer Discovery · 2016 · 239 citations · Full text

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

Margarida A. Santos, Robert B. Faryabi, Aysegul V. Ergen et al. · Nature · 2014 · 203 citations · Full text

Hematological Malignancy, Chromatin, Dna Damage +6

AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes

Aniruddha J. Deshpande, Anagha Deshpande, Amit Sinha et al. · Cancer Cell · 2014 · 181 citations · Full text

Hox Gene Expression, Diverse Aml Subtypes, Epigenetic Change +7