Tomoko Obara

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

Matias Simons, Joachim Gloy, Athina Ganner et al. · Nature Genetics · 2005 · 756 citations

Life Sciences, Genetics, Molecular Biology +11

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

Edgar A. Otto, Bernhard Schermer, Tomoko Obara et al. · Nature Genetics · 2003 · 642 citations · Full text

Medicine, Genetics, Molecular Genetics +14

Polycystin-1, STAT6, and P100 Function in a Pathway that Transduces Ciliary Mechanosensation and Is Activated in Polycystic Kidney Disease

Seng Hui Low, Shivakumar Vasanth, Claire H. Larson et al. · Developmental Cell · 2006 · 366 citations · Full text

Life Sciences, Cell Biology, Nephrology +13

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

Sehyun Kim, Norann A. Zaghloul, Ekaterina Bubenshchikova et al. · Nature Cell Biology · 2011 · 255 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

Shanming Liu, Tomoko Obara, Shiei Kuida et al. · Development · 2002 · 251 citations

Life Sciences, Genetics, Molecular Genetics +17