Karin Pchalek

Tricyclic [1,2,4]Triazine 1,4-Dioxides As Hypoxia Selective Cytotoxins

Michael P. Hay, Kevin O. Hicks, Karin Pchalek et al. · Journal of Medicinal Chemistry · 2008 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis of activated 3-substituted indoles: an optimised one-pot procedure

Karin Pchalek, Ashley Jones, Monique M. T. Wekking et al. · Tetrahedron · 2004 · 51 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Hypoxia-Selective 3-Alkyl 1,2,4-Benzotriazine 1,4-Dioxides: The Influence of Hydrogen Bond Donors on Extravascular Transport and Antitumor Activity

Michael P. Hay, Karin Pchalek, Frederik B. Pruijn et al. · Journal of Medicinal Chemistry · 2007 · 43 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Pharmacokinetic/Pharmacodynamic Model-Guided Identification of Hypoxia-Selective 1,2,4-Benzotriazine 1,4-Dioxides with Antitumor Activity: The Role of Extravascular Transport

Michael P. Hay, Kevin O. Hicks, Frederik B. Pruijn et al. · Journal of Medicinal Chemistry · 2007 · 38 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Stille Coupling Reactions in the Synthesis of Hypoxia-Selective 3-Alkyl-1,2,4-Benzotriazine 1,4-Dioxide Anticancer Agents

Karin Pchalek, Michael P. Hay · The Journal of Organic Chemistry · 2006 · 38 citations

Natural Sciences, Chemistry, Oncology +12