Nikiana Simigdala

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Lesley‐Ann Martin, Ricardo Ribas, Nikiana Simigdala et al. · Nature Communications · 2017 · 158 citations · Full text

Medicine, Genetics, Oncology +17

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

Nikiana Simigdala, Qiong Gao, Sunil Pancholi et al. · Breast Cancer Research · 2016 · 139 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci

Joseph S. Baxter, Olivia C. Leavy, Nicola H. Dryden et al. · Nature Communications · 2018 · 133 citations · Full text

Life Sciences, Genetics, Oncology +15

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

Élodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd et al. · Nature Communications · 2020 · 124 citations · Full text

Medicine, Oncology, Pharmacology +17

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

Sunil Pancholi, Ricardo Ribas, Nikiana Simigdala et al. · Oncogene · 2020 · 91 citations · Full text

Medicine, Molecular Biology, Oncology +17