Lesley‐Ann Martin

Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer

María Teresa Herrera-Abreu, Marta Palafox, Uzma Asghar et al. · Cancer Research · 2016 · 779 citations · Full text

Medicine, Cancer Biology, Oncology +17

Analysis of <i>ESR1</i> mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

Gaia Schiavon, Sarah Hrebien, Isaac García-Murillas et al. · Science Translational Medicine · 2015 · 564 citations · Full text

Medicine, Molecular Biology, Oncology +14

Enhanced Estrogen Receptor (ER) α, ERBB2, and MAPK Signal Transduction Pathways Operate during the Adaptation of MCF-7 Cells to Long Term Estrogen Deprivation

Lesley‐Ann Martin, Ian Farmer, Stephen Johnston et al. · Journal of Biological Chemistry · 2003 · 295 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Lesley‐Ann Martin, Ricardo Ribas, Nikiana Simigdala et al. · Nature Communications · 2017 · 158 citations · Full text

Medicine, Genetics, Oncology +17

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

Christina M.W. Chan, Lesley‐Ann Martin, Stephen Johnston et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2002 · 150 citations

Medicine, Cancer Biology, Oncology +12