Aykut Üren

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

Hayriye V. Erkizan, Yali Kong, Melinda S. Merchant et al. · Nature Medicine · 2009 · 435 citations · Full text

Oncogenic Agent, Pathology, Tumor Suppressor +4

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action

Paul W. Finch, Xi He, Michael J. Kelley et al. · Proceedings of the National Academy of Sciences · 1997 · 413 citations · Full text

Secreted Frizzled-related Protein-1 Binds Directly to Wingless and Is a Biphasic Modulator of Wnt Signaling

Aykut Üren, Frieda Reichsman, Vasiliki Anest et al. · Journal of Biological Chemistry · 2000 · 412 citations · Full text

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

Elspeth M. Beauchamp, Lymor Ringer, Gülay Bulut et al. · Journal of Clinical Investigation · 2010 · 343 citations · Full text

Gli Transcription Factors, Cancer Biology, Glioma +16

Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma

Chand Khanna, Timothy M. Fan, Richard Görlick et al. · Clinical Cancer Research · 2014 · 198 citations · Full text