Joseph Ramcharan

Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.

S.E. Greasley, Patricia A. Horton, Joseph Ramcharan et al. · Nature Structural Biology · 2001 · 82 citations

Crystal Structure, Biosynthesis, Biochemistry +7

Analysis of Imatinib and Sorafenib Binding to p38α Compared with c-Abl and b-Raf Provides Structural Insights for Understanding the Selectivity of Inhibitors Targeting the DFG-Out Form of Protein Kinases

H.V.M. Namboodiri, Marina Bukhtiyarova, Joseph Ramcharan et al. · Biochemistry · 2010 · 70 citations

Sorafenib Binding, Drug Target, Kinase Inhibitors +18

Histone H2AX Is Phosphorylated at Sites of Retroviral DNA Integration but Is Dispensable for Postintegration Repair

René Daniel, Joseph Ramcharan, Emmy P. Rogakou et al. · Journal of Biological Chemistry · 2004 · 54 citations · Full text

Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren et al. · Bioorganic & Medicinal Chemistry · 1997 · 22 citations

Medicinal Chemistry, Medicine, Gar Tfase +10

Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors

Dale L. Boger, Monica J. Kochanny, Hui Cai et al. · Bioorganic & Medicinal Chemistry · 1998 · 18 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9