João Filipe Neves

Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products

M. Wolter, Pim J. de Vink, João Filipe Neves et al. · Journal of the American Chemical Society · 2020 · 59 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Fragment-based Differential Targeting of PPI Stabilizer Interfaces

X. Guillory, M. Wolter, S. Leysen et al. · Journal of Medicinal Chemistry · 2020 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Sebastian A. Andrei, Femke A. Meijer, João Filipe Neves et al. · ACS Chemical Neuroscience · 2018 · 34 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Phosphorylated full‐length Tau interacts with 14‐3‐3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14‐3‐3 dimer

João Filipe Neves, Olívia Petrvalská, Francesco Bosica et al. · FEBS Journal · 2020 · 28 citations · Full text

Life Sciences, Biochemistry, Neuroscience +15

Set-up and screening of a fragment library targeting the 14-3-3 protein interface

Dario Valenti, João Filipe Neves, François‐Xavier Cantrelle et al. · MedChemComm · 2019 · 21 citations

Life Sciences, Biochemistry, Molecular Biology +16