Tyrone DeSpenza

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

Sheng Chih Jin, Weilai Dong, Adam J. Kundishora et al. · Nature Medicine · 2020 · 154 citations · Full text

Neuro-oncology, Developmental Biology, Ependyma +15

De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus

Charuta G. Furey, Jungmin Choi, Sheng Chih Jin et al. · Neuron · 2018 · 151 citations · Full text

De Novo Mutation, Developmental Biology, Ependyma +14

Hyperactivity of Newborn Pten Knock-out Neurons Results from Increased Excitatory Synaptic Drive

Michael R. Williams, Tyrone DeSpenza, Meijie Li et al. · Journal of Neuroscience · 2015 · 136 citations · Full text

The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus

Stephanie M. Robert, Benjamin C. Reeves, Emre Kiziltug et al. · Cell · 2023 · 129 citations · Full text

Inflammation, Csf Dysregulation, Ependyma +13

Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus

Phan Q. Duy, Stefan Weise, Claudia Marini et al. · Nature Neuroscience · 2022 · 96 citations · Full text

Neuroregeneration, Developmental Biology, Brain Structure +12