Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

Scott Gettinger, Jungmin Choi, Katherine Hastings, +23

Cancer Discovery

Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis

Ila Datar, Miguel F. Sanmamed, Jun Wang, +22

Clinical Cancer Research

A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

Scott Gettinger, Jungmin Choi, Nikita Mani, +19

Nature Communications

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

Sheng Chih Jin, Weilai Dong, Adam J. Kundishora, +58

Nature Medicine

Neuro-oncologyDevelopmental BiologyEpendymaPediatric HydrocephalusBrain Development +13

Integrated mutational landscape analysis of uterine leiomyosarcomas

Jungmin Choi, Aránzazu Manzano, Weilai Dong, +41

Proceedings of the National Academy of Sciences

Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus

Phan Q. Duy, Stefan Weise, Claudia Marini, +64

Nature Neuroscience

NeuroregenerationDevelopmental BiologyBrain StructureNeuroanatomyNeuroprogenitor-based Genetic Subtype +10

Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors

Charles H. Li, Elena Bonazzoli, Stefania Bellone, +36

Proceedings of the National Academy of Sciences

Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy

Luca Zammataro, Salvatore Lopez, Stefania Bellone, +42

Proceedings of the National Academy of Sciences

Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology

Norman G. Nicolson, Timothy D. Murtha, Weilai Dong, +11

The Journal of Clinical Endocrinology & Metabolism

Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation

Daniel Durán, Xue Zeng, Sheng Chih Jin, +44

Neuron

ChromatinDevelopmental BiologySomatic VariantGenetic DisorderMedicine +10